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A single-centre, double-blind trial randomized 53 adults aged 60–80 with low fibre intake to a daily fibre-enriched bread roll (10 g added fibre; n=28) or a matched bread roll (n=25) for 12 weeks. Forty-nine participants were included in the cognitive analysis.

The randomized BiomeBakery feasibility study assigned 53 older adults without dementia and with low habitual fibre intake to bread containing an additional 10 g/day prebiotic fibre blend or control bread for 12 weeks. Cognitive analyses included 49 participants; researchers also assessed adherence, mood, gastrointestinal outcomes and peripheral biomarkers.

This feasibility study was small and was not designed to establish efficacy. Baseline-adjusted sensitivity analyses found no significant intervention effects on cognitive outcomes; the MoCA memory contrast weakened to a trend. One author was affiliated with Myota Limited, and the article identifies Puratos as the bread manufacturer.

The placebo group’s MoCA memory subscore increased more in an unadjusted comparison; after baseline adjustment, that contrast weakened to a trend. Other cognitive outcomes showed no significant intervention effect. Average adherence was about 98%; the study primarily evaluated feasibility.

Limits and disclosures

The intervention was a specific bread product, and the sample and follow-up were intended for feasibility rather than definitive efficacy. One author’s affiliation includes Myota Limited, a company named in the paper; readers should treat any efficacy signal as preliminary.

This sourced news summary and translation were prepared with AI assistance. Source links, the news date and research limitations are disclosed; this is not a claim of independent medical expert review. News production method.

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