Research · Neuroscience · Safety
Follow developments in nootropics and brain research with their sources and limitations. We explain what a new finding says, and what it cannot establish.
128 published articles
Research
In an Ecuadorian randomized trial of 215 pregnancies, a food-diversity program was associated with growth differences in several fetal brain structures; the study measured anatomy, not later cognition.
Research
A 24-week randomized trial in 87 people with early cognitive impairment found lower pTau181 and selective visuospatial signals, but no MMSE, verbal-memory or executive-score difference.
neuroscience
In 31 young adults, EEG during word–object learning linked stronger theta activity with later sleep-wave coupling and memory retention after a nap; the association does not establish causation.
neuroscience
In an fMRI experiment, retrieval prompts shaped later neural patterns for learned image–word pairs, even though participants performed similarly on the memory test.
Safety
FDA reported adverse events in at least 30 patients after compounded IV glutathione and warned against using supplement-grade material for injections.
Research
A 70-person randomized Parkinson trial found short-term walking-speed and later freezing-of-gait signals from stimulation plus treadmill training, but no sustained overall advantage.
Research
In a randomized trial of young men, six hours of simulated hypoxia at 4,500 m did not alter psychobiological measures, and glutamine supplementation did not produce a detectable benefit.
neuroscience
An August NIH report highlighted altered DNA contacts and gene activity in postmortem prefrontal cells from Alzheimer’s donors; the study does not establish causality.
Research
A 12-week peanut trial in 27 older adults with memory complaints found no significant group differences in cognition, brain activation or adjusted biomarkers.
neuroscience
Manipulating wake-responsive neurons in mice altered NREM sleep and sleep pressure, identifying candidate circuits for sleep regulation without showing that reduced sleep is safe.
neuroscience
NIH reported that stem-cell-derived brain organoids matured over nearly six years, with molecular age tracking elapsed time; these are laboratory models.
neuroscience
During a delayed-match task, mice reused prefrontal and parietal neural subspaces for stimulus processing and memory maintenance. Data-constrained network models supported a modular account, but the result concerns one task and does not prove human cognitive modules.