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Study design

In a randomized, double-masked trial, 116 adults received either a C4 energy drink or a control beverage, each providing 200 mg caffeine. Researchers tested participants before and about 45 minutes after the drink. The comparison asked whether the multi-ingredient formula added an acute effect beyond matched caffeine.

Findings

Both drinks improved psychomotor-vigilance reaction time from baseline, but the changes did not differ significantly between groups. The energy-drink group’s MemTrax correct percentage fell and reaction time rose; the control group showed no matching within-group shift, yet the between-group contrast was not significant. The authors reported no difference between drinks in sustained attention, memory, grip strength or wall-sit endurance.

Limitations and disclosures

This was one acute session and cannot establish long-term cognition, habitual-use effects or safety. One brand formula cannot represent all energy drinks, and the abstract omitted between-group effect sizes. Jose Antonio is a paid scientific advisor to Create Wellness, Bear Balanced, AlzChem Group and ENHANCED Games; the other authors reported no conflicts.

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Research news is not medical advice or a recommendation to use a substance. Read findings in the context of the study design, participants and limitations. Editorial standards.

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